Ovarian cysts and tumors as the cause of isosexual pseudoprecocious puberty

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چکیده

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Refractory Hypertension and Isosexual Pseudoprecocious Puberty Associated with Renin-Secreting Ovarian Steroid Cell Tumor in a Girl

Steroid cell tumor, not otherwise specified (NOS), are rare ovarian tumor, in addition, it is more rare in children. The majority of these tumors produce several steroid hormones, particularly testosterone. Estrogen also secreted by steroid cell tumor, NOS, but it is uncommon. Furthermore, hypertension is an infrequent sign in steroid cell tumor, NOS. An 8.5-yr-old girl with hypertension and fr...

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A Rare Cause of Precocious Puberty and Massive Ovarian Cysts Associated with Hypothyroidism

Van Wyk-Grumbach syndrome (VWGS) is characterized by juvenile hypothyroidism, delayed bone age, isosexual precocious puberty and massive ovarian cysts. We report such a case in a 7-yearold girl who presented with a bilateral pelvic pain, abdominal distension and signs of hypothyroidism. Physical examination showed a breast development and lack of pubic and axillary hair. There was no clitoromeg...

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A Case of Virilizing Adrenocortical Adenoma

SUMMARY A 2/12 Year-old boy with IsoSexual Pseudoprecocious puberty due to a Virilizing Adrenocortical adenoma is presentecl, who was crronously treated as CAH for 9 months. Prevalence, clinical presentation, diagnosis and differential diagnosis of these tumors are discussed briefly.

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Precocious puberty and ovarian tumors – 2 case reports

Results Case 1 3 years old girl presented with progressive bilateral breast enlargement over 1 year, irregular vaginal bleeding for 10 months and pubic hair development for 2 months. Her past history was unremarkable. Her general examination and vitals were normal. Tanners staging was B3P3. There was no axillary hair or genital ambiguity. Cardiac, thoracic and neurological examinations were nor...

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Aromatase p450 expression in a feminizing adrenal adenoma presenting as isosexual precocious puberty.

A 7-yr-old girl presented with isosexual precocious puberty secondary to a feminizing adrenal adenoma. The adrenal tumor was found to express aromatase messenger ribonucleic acid. Enzyme kinetic studies revealed a high level of aromatase activity in the adrenal tumor, with a K(m) of 45 nmol/L and a maximum velocity of 25.6 pmol/mg.h. Aromatase activity was approximately 500-fold higher in the t...

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ژورنال

عنوان ژورنال: Srpski arhiv za celokupno lekarstvo

سال: 2006

ISSN: 0370-8179,2406-0895

DOI: 10.2298/sarh0608305m